The maximum concentration7 mg / ml. Depending on the speed of injection and infusion purposes of approximately 5-6 hours after administration of the drug excreted by the kidneys . With bile. A small amount is accumulated in the reticuloendothelial system (without exhibiting toxic effects on the liver, lungs, spleen and lymph nodes) where amylase is cleaved.
Anavar for women and treatment of hypovolemia and shock during operations, acute blood loss, trauma, infections and burns;
– Hypersensitivity to the starch or other ingredients;
– heart failure decompensation stage;
– Renal failure with oliguria or anuria (creatinine> 2 mg / dl or, respectively, ., 177 pM / l)
– cardiogenic pulmonary edema
– intracranial bleeding;
– expressed bleeding disorders;
– compensated chronic heart, liver and kidney failure;
– hemorrhagic diathesis;
– intracranial hypertension.
Pregnancy and lactation
Although established that anavar for women does not have embryotoxic and teratogenic effects, the use of the drug in the first trimester of pregnancy is not desirable. In the 2nd and 3rd trimesters of pregnancy can be used only for health reasons.
It is not known whether allocated in breast milk, therefore caution should be exercised in the appointment of the drug to women during lactation.
Administered in an intravenous infusion. In the absence of other provisions of the drug is administered intravenously, in accordance with the need forreplacement of the volume of circulating plasma . Considering the possible anaphylactic reactions, the first 10-20 ml of the product anavar for women should be administered slowly, with careful monitoring of the patient’s condition. Note risk of overloading in the circulatory system too rapidly or too high a dose of the drug. The daily dose intravenous and speed are calculated according to the hemorrhage, hemoglobin concentration and hematocrit. In young patients, without the risk of cardiovascular or pulmonary complications limit the application of colloidal drug obemzameschayuschego considered hematocrit less than 30%.
The maximum rate of infusion depends on baseline hemodynamics and is about 20 ml / kg / hr.
The maximum daily dose of 20 ml / kg / day (2 g HES / kg / day).
Rovedenie hemodilution can be performed under conditions izovolemii (s bloodletting) or hypovolemia (no bleeding).
The daily dose and rate of intravenous administration:
– low dose – once 250 ml / day for 0.5-2 hours,
– average dose – once 500 ml / day for 4-6 hours,
– high dose – twice with 500 ml / day for 8-24 hours.
The duration of treatment depends on the indication and the bCC.
Due effect hemodilution infusion lead, depending on the dose, a decrease in hematocrit and plasma protein concentration of the blood. Also due to this effect may transient increase in blood clotting time and bleeding time, but in this case no effect on platelet function and clinically significant bleeding does not occur.
Prolonged daily administration anavar for women in the medium and high doses can often cause itching, which difficult to cupping. It may appear a few weeks after the end of treatment and persist for a long time.
The literature describes the relationship between the dose and frequency of itching at otoneurological diseases such as sudden hearing loss, tinnitus. In these diseases to reduce incidence of itching recommend limiting the dose to the maximum daily